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探讨米索前列醇用于足月妊娠引产的可行性及对母儿的安全性。方法 对50例足月妊娠单胎头位初产妇,30例足月妊娠单胎头位经产妇,用米索前列醇口服0.05mg每小时一次,直到规律宫缩,胎儿娩出,进行引产(米索组),以同样例数,同等条件孕妇,用催产素为对照(催产素组)。结果 米索组及对照组引产成功率分别为98.75％和81.25％,P<0.01有显著性差异。两组12小时分娩成功率分别为87.5％和62.5％,P<0.01有显著差异。两组失败率分别为1.25％和18.75％,P<0.01有显著差异。结论 小剂量米索前列醇口服用于足月妊娠引产疗效显著,安全、方便、有推广价值。
To investigate the feasibility of misoprostol for induction of labor in full-term pregnancy and the safety of mother and child. Methods 50 cases of full-term pregnancy single-head primipara, 30 cases of full-term pregnancy single head position of the mother, with oral misoprostol 0.05mg once per hour, until the regular contractions, the fetus was delivered for induction of labor Cable group), the same number of cases, the same conditions pregnant women, with oxytocin as the control (oxytocin group). Results Misoprostol and control group, the success rate of induction of labor was 98.75% and 81.25%, P <0.01 significant difference. The 12-hour delivery rates in both groups were 87.5% and 62.5%, respectively, with significant differences at P <0.01. The failure rates of the two groups were 1.25% and 18.75%, respectively, with significant differences at P <0.01. Conclusion Small doses of misoprostol for induction of full-term pregnancy induction of labor is significant, safe, convenient and has promotional value.