弥漫性脂肪瘤病(madelung’s disease)是少见的良性肿瘤,病变自皮下组织侵入到筋膜、肌肉,使整个病变区域呈弥散性脂肪堆积。临床上表现为多发的、无痛性、无包膜的脂肪瘤,多分布于颈部、枕部、肩部和其他躯干部位,严重时可影响人体正常的生理功能~([1-4])。本病最早是由Benjamin Brodie在1846年首次报道~([5]),该病有几种不同的命名,如Madelung’s病、Lanois-Bensaude综合征、良性对称性脂肪瘤病(benign symmetrical lipomatosis,BSL)、对称性腺脂瘤病(symmetrical adenolipomatosis)或单 Madelung’s disease is a rare benign tumor that invading into the fascia and muscle from the subcutaneous tissue, causing the accumulation of diffuse fat throughout the diseased area. Clinical manifestations of multiple, painless, non-enveloped lipoma, mostly in the neck, occipital, shoulder and other torso parts, serious cases can affect the normal physiological function of the body ~ ([1-4] ). This disease was first reported by Benjamin Brodie in 1846 ~ ([5]). The disease has several different names, such as Madelung’s disease, Lanois-Bensaude syndrome, benign symmetrical lipomatosis (BSL ), Symmetrical adenolipomatosis or single