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采用1:3配对病例对照研究方法探讨了痛风致病因素及其相互关系。病例选自近2年内在山东医科大学附属医院确诊的痛风患者26名,每个病例按1:3配比选择对照,要求对照与病例年龄相同(相差5岁之内),性别相同,与病例来自同一地区,无自身免疫性疾病和恶性肿瘤病史。按统一调查表询问调查。用Egreat软件分析,单因素分析显示,有11个因素与痛风发病相关,有7个因素在P=0.05水平被选入多因素模型。它们依次是:食海产品(OR=9.267),高血压(OR=6.401),寒冷与潮湿(OR=4.558),肾脏疾患(OR=2.864),自身免疫性疾病家族史(OR=2.730),食肉(OR=2.317)和饮茶(OR=0.319)。
A 1: 3 paired case-control study was used to explore the causative agents of gout and their relationship. The patients were selected from 26 gout patients diagnosed in the Affiliated Hospital of Shandong Medical University in the recent 2 years. Each patient was selected according to the ratio of 1: 3, and the control was the same as the age of the patients (within 5 years of age). The same sex, Coming from the same area without a history of autoimmune diseases and malignancies. According to the unified questionnaire survey. With Egreat software analysis, univariate analysis showed that there were 11 factors associated with the incidence of gout. Seven factors were selected for the multivariate model at P = 0.05. (OR = 9.240), cold and humid (OR = 4.558), kidney disease (OR = 2.864), family history of autoimmune diseases (OR = 2.730) Carnivorous (OR = 2.317) and tea (OR = 0.319).