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目的:探讨老年慢性肾功能衰竭(CRF)的透析指征。方法:根据开始透析时的内生肌酐清除率(Ccr),将60例老年CRF患者分为早期透析组和对照组,观察两组治疗前后的血压、血生化指标、再次住院情况和生存率。结果:早期透析组Ccr 12.1±1.1ml/min(糖尿病肾病Ccr17.6±1.7ml/min)开始透析治疗,对照组Ccr 5.7±1.4ml/min(糖尿病肾病9.0±3.1ml/min)。经治疗早期透析组平均动脉压(MAP)明显低于对照组,血红蛋白(Hb)及血白蛋白(ALB)明显高于对照组。早期透析组的1年生存率明显高于对照组,住院次数及平均住院天数均明显低于对照组。结论:老年CRF患者宜早期透析治疗。
Objective: To investigate the dialysis indications of senile chronic renal failure (CRF). Methods: According to the rate of endogenous creatinine clearance (Ccr) at the beginning of dialysis, 60 elderly CRF patients were divided into early dialysis group and control group. Blood pressure, blood biochemical indexes, rehospitalization and survival were observed before and after treatment. Results: In dialysis group, Ccr 12.1 ± 1.1ml / min (Diabetic nephropathy Ccr17.6 ± 1.7ml / min) started dialysis treatment, and Ccr of control group 5.7 ± 1.4ml / min (Diabetic nephropathy 9.0 ± 3.1ml / min). After treatment, the mean arterial pressure (MAP) in the early dialysis group was significantly lower than that in the control group, and the levels of hemoglobin (Hb) and albumin (ALB) were significantly higher than those in the control group. The 1-year survival rate of the early dialysis group was significantly higher than that of the control group, the number of hospitalizations and the average length of stay were significantly lower than the control group. Conclusion: Elderly patients with CRF should be treated early dialysis.