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目的探讨托吡酯片单药治疗小儿癫痫的临床效果。方法从本院2010年10月~2013年10月收治的小儿癫痫患者中随机选择80例进行研究,按照治疗情况分为两组,分别采用托吡酯片单药治疗和常规抗癫痫治疗加用托吡酯片治疗。结果所有患儿在治疗过程中均未出现严重的不良反应,观察组的治疗总有效率为90.0%,显著高于对照组的70.0%,(P<0.05)。结论托吡酯片单药治疗小儿癫痫安全可靠,疗效确切,值得推广。
Objective To investigate the clinical effect of topiramate tablets in the treatment of epilepsy in children. Methods From October 2010 to October 2013 in our hospital, 80 cases of children with epilepsy were randomly selected to study, according to the treatment of patients were divided into two groups were treated with topiramate tablets and conventional antiepileptic treatment plus topiramate tablets treatment. Results All patients had no serious adverse reactions during the treatment. The total effective rate in the observation group was 90.0%, which was significantly higher than that in the control group (70.0%, P <0.05). Conclusion Topiramate tablets in children with epilepsy treatment is safe and reliable, effective, it is worth promoting.