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目的分析冠状动脉慢血流(SCF)发生的危险因素。方法选取2006—2013年迁安市人民医院冠状动脉造影患者185例,根据TIMI帧计数(TFC)法指标不同分为SCF组75例与对照组110例。SCF组为冠状动脉正常但冠状动脉血流缓慢患者,对照组为冠状动脉正常且血流速度正常患者。比较两组患者入院后的临床资料及血液化验指标(空腹血糖、血脂、血小板计数、尿酸及同型半胱氨酸)。通过Logistic回归分析探讨SCF发生的危险因素。结果 SCF组患者男性占比、吸烟率、尿酸水平、同型半胱氨酸水平均高于对照组,差异有统计学意义(P<0.05)。两组患者年龄、糖尿病史、高血压史、血小板计数、空腹血糖、低密度脂蛋白胆固醇、总胆固醇、三酰甘油、高密度脂蛋白胆固醇水平比较,差异无统计学意义(P>0.05)。Logistic回归分析结果显示,吸烟、高尿酸、高同型半胱氨酸水平是SCF发生的独立危险因素。结论吸烟、高尿酸和高同型半胱氨酸水平是SCF发生的危险因素。
Objective To analyze the risk factors of coronary artery slow flow (SCF). Methods 185 cases of coronary angiography in Qian’an People’s Hospital from 2006 to 2013 were selected and divided into 75 cases in SCF group and 110 cases in control group according to TIMI frame count (TFC) method. SCF group was normal coronary artery but slow coronary flow, the control group was normal coronary artery and normal blood flow velocity. The clinical data and blood tests (fasting blood glucose, blood lipids, platelet count, uric acid and homocysteine) were compared between the two groups after admission. Logistic regression analysis to explore the risk factors of SCF. Results The proportions of male, smoking, uric acid and homocysteine in SCF group were significantly higher than those in control group (P <0.05). There were no significant differences in age, history of diabetes, history of hypertension, platelet count, fasting blood glucose, low density lipoprotein cholesterol, total cholesterol, triglyceride and high density lipoprotein cholesterol between the two groups (P> 0.05). Logistic regression analysis showed that smoking, high uric acid, high homocysteine levels were independent risk factors for SCF. Conclusion Smoking, high uric acid and high homocysteine levels are risk factors for SCF.