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目的探讨社区门诊应用阿奇霉素抗感染治疗急性支气管炎的有效性。方法选取深圳市宝安区西乡人民医院2012年7月至2014年9月收治的160例急性支气管炎患者作为研究对象,按照随机数字表法均分两组,每组80例。两组患者均给予我社区门诊针对支气管炎的常规治疗及护理措施,同时对照组患者给予口服头孢丙烯分散片抗感染治疗,研究组给予口服阿奇霉素分散片抗感染治疗,治疗1个疗程后,对两组临床疗效、症状体征改善情况及血常规指标进行综合比较。结果研究组临床治愈率达到86.25%,明显高于对照组(71.25%,P<0.05),同时研究组肺部啰音消失及咳痰消退所需时间明显少于对照组(P<0.05),经1个疗程治疗后,研究组平均白细胞计数、中心粒细胞百分比、两项血常规指标及C-反应蛋白检测结果均优于对照组(P<0.05)。结论针对社区急性支气管炎患者,应用阿奇霉素辅助抗感染治疗能迅速改善患者咳痰及肺部啰音,疗效显著,值得在临床推广应用。
Objective To investigate the effectiveness of azithromycin anti-infection in community clinics for the treatment of acute bronchitis. Methods A total of 160 patients with acute bronchitis admitted from July 2012 to September 2014 in Xixiang People’s Hospital of Bao’an District of Shenzhen City were enrolled in this study. All patients were divided into two groups according to a random number table. Two groups of patients were given my community outpatient treatment for conventional bronchitis and nursing interventions, while patients in the control group were given oral cefprozil dispersible tablets anti-infective treatment, the study group was given oral azithromycin dispersible tablets anti-infective treatment, after a course of treatment, the Two groups of clinical efficacy, improvement of symptoms and signs and blood parameters were compared. Results The clinical cure rate of the study group was 86.25%, which was significantly higher than that of the control group (71.25%, P <0.05). At the same time, the time required for the disappearance of pulmonary rales and the disappearance of expectoration of sputum in the study group was significantly less than that of the control group (P <0.05) After one course of treatment, the average leucocyte count, the percentage of neutrophils, the two blood tests and the C-reactive protein in the study group were all better than those in the control group (P <0.05). Conclusion Acute bronchitis patients with azithromycin-assisted anti-infection treatment can rapidly improve sputum and pulmonary rales in patients with significant effect, it is worth in the clinical application.