目的 :提高对Castleman病的认识。方法 :报告 6例Castleman病并复习有关文献。结果 :该病临床表现取决于受累的部位。例 1和例 2以表浅淋巴结肿大为其临床表现 ;例 3和例 4以肾区不适为其主诉 ,早期诊断困难 ;例 5和例 6为中心性Castleman病 ,临床表现复杂 ,早期均误诊为结缔组织病 ,分别在起病 2年和 3年后才确诊。结论 :重视淋巴结活检是早期诊断的关键 Objective: To raise awareness of Castleman’s disease. Methods: Six cases of Castleman’s disease were reported and reviewed. Results: The clinical manifestations of the disease depend on the affected site. Cases 1 and 2 showed superficial lymph nodes as their clinical manifestations; cases 3 and 4 complained of renal discomfort, early diagnosis was difficult; cases 5 and 6 were central Castleman’s disease with complicated clinical manifestations and early stage Misdiagnosed as connective tissue disease, were diagnosed in 2 years and 3 years after onset. Conclusion: The importance of lymph node biopsy is the key to early diagnosis