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目的：探讨鞘内使用丁胺卡那霉素治疗颅内感染的方法及临床疗效，对15例颅内感染患者采用丁胺卡那霉素80.0mg,每次用生理盐水稀释至5ml，经腰椎穿刺鞘内注射，1次/天，至患者体温及脑脊液中白细胞恢复正常。结果治愈10例，好转4例，死亡1例，病死率6.0%，预后良好率达94%，结论丁胺卡那霉素鞘内注射治疗颅内感染能取得满意疗效。“,”Objective To explore the use of agmatine Cara kanamycin treatment method and clinical effect of intrathecal intracranial infection, 15 cases of intracranial infection were treated with amikacin, Cara amphotericin 80.0mg, each diluted with normal saline to 5ml, after lumbar puncture intrathecal injection, 1 times / day, and white blood cels in cerebrospinal fluid in patients with normal body temperature and. Results 10 cases were cured, 4 cases improved, 1 cases died, the mortality rate of 6%, prognostic and good rate was 94%, conclusion: butylamine Cara mycomycin intrathecal injection for the treatment of intracranial infection can achieve satisfactory effect.