本文报道吡喹酮对慢性日本血吸虫病的临床及免疫学参数的效用。2例日本病人都具有针对日本血吸虫抗原的高滴度抗体,但粪便里无虫卵,无或仅有轻微的症状,均用吡喹酮治疗,每日剂量分别为50mg/kg和40mg/kg。治疗后的0、1、3、6、12和24个月的冰冻保存血清用血吸虫虫卵和成虫抗原同时 This article reports the utility of praziquantel in clinical and immunological parameters of chronic schistosomiasis japonica. Two Japanese patients had high titers against Schistosoma japonicum antigens, but no eggs in the stool, with or without minor symptoms, were treated with praziquantel at daily doses of 50 mg / kg and 40 mg / kg . Cryopreserved serum at 0, 1, 3, 6, 12, and 24 months after treatment was treated with schistosome eggs and adult antigens simultaneously