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目的 :探讨米非司酮治疗子宫肌瘤的效果。方法 :74例确诊子宫肌瘤的患者 ,口服米非司酮 12 5mg/d ,3个月。治疗前后B超监测子宫及肌瘤体积、血常规、血雌孕激素水平。结果 :患者在治疗期间均出现闭经 ,症状消失。子宫及肌瘤体积平均缩小 36 2 7%及 5 6 2 0 % ,血红蛋白恢复正常 ,孕激素下降明显 (P <0 0 1) ,雌激素无明显变化。结论 :米非司酮治疗子宫肌瘤有一定效果 ,副作用小 ,是一种可行的保守治疗方法。
Objective: To investigate the efficacy of mifepristone in the treatment of uterine fibroids. Methods: 74 patients diagnosed with uterine fibroids, oral mifepristone 125mg / d, 3 months. B-monitoring before and after treatment of uterine and fibroid volume, blood, serum estrogen and progesterone levels. Results: All patients had amenorrhea during treatment, and the symptoms disappeared. The volume of uterus and fibroids decreased by 36.27% and 56.20% on average, hemoglobin returned to normal, progesterone decreased significantly (P <0.01), and estrogen had no significant change. Conclusion: Mifepristone treatment of uterine fibroids have some effects, side effects, is a viable conservative treatment.