目的 :报告 11例垂体腺瘤经口—鼻蝶窦入路显微镜下手术治疗体会。方法 :本文对 11例经口鼻蝶窦入路 ,在显微镜下切除肿瘤的手术治疗作回顾性分析。结果 :全组无 1例死亡 ,视力、视野恢复或好转的 6例 ,6例术后有暂时性尿崩症 ,1例术后副鼻窦炎。 8例随访 6个月至 3年 ,未见肿瘤复发。结论 :本组病例表明 ,垂体腺瘤经口鼻蝶窦入路显微镜下手术治疗 ,术后恢复快 ,并发症少 ,复发率低 ,是安全有效的手术方法 Objective: To report the surgical treatment of 11 cases of pituitary adenomas undergoing oral-nasal spheno-sinus approach. Methods: A retrospective analysis of 11 cases of oral and nasal sphenoid sinus surgery in the surgical resection of the tumor under a microscope. Results: There was no one case of death, visual acuity, visual field recovery or improvement in 6 cases, 6 cases of postoperative temporary diabetes insipidus, 1 case of postoperative sinusitis. 8 cases were followed up for 6 months to 3 years, no tumor recurrence. Conclusion: This group of patients showed that pituitary adenomas were treated under the microscope of the mouth, nose and sphenoid sinus. It is a safe and effective surgical method to recover the pituitary adenomas quickly, with less complications and low recurrence rate