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本文采用M型超声心动图对112例原发性高血压患者和104例正常对照者作了观察。超声测量值经年龄和体表面积校正后,患者中73％示左室后壁或室间隔厚度增加,12％呈非对称性室间隔肥厚;58％呈左室心肌重量指数异常增加,反映左室收缩功能的喷血分数和平均周径纤维缩短率及反映左室舒张功能的二尖瓣EF速度和舒张早期径纤维伸长速度也显著低于正常对照。多因素逐步回归分析显示原发性高血压患者的左室心肌重量和形态改变是影响左室收缩功能的主要因素。结果提示:超声心动图对左室肥厚的估计较心电图或X线优越,使早期检出率大大提高,并可通过对左室收缩和舒张功能的定量测定提高临床对离血压性心脏损伤的估计能力。
In this paper, 112 patients with essential hypertension and 104 normal controls were observed by M-mode echocardiography. Ultrasound measurements were corrected for age and body surface area, 73% of patients showed increased thickness of the left ventricular posterior wall or interventricular septum, 12% showed asymmetric ventricular septal hypertrophy; 58% showed an abnormal increase in left ventricular myocardial mass index, reflecting left ventricular Systolic ejection fraction and mean circumferential fiber shortening rate and reflect the left ventricular diastolic mitral EF velocity and diastolic diameter fiber elongation rate was significantly lower than the normal control. Multi-factor regression analysis showed that left ventricular systolic function was the main factor influencing left ventricular myocardial mass and morphological changes in patients with essential hypertension. The results suggest that the echocardiographic assessment of left ventricular hypertrophy is superior to either electrocardiogram or X-ray and greatly improve the early detection rate and may improve the clinical estimate of blood pressure-induced cardiac injury by quantitatively measuring left ventricular systolic and diastolic function ability.