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目的 研究儿童反复呼吸道感染 (RRTI)形成的易感因素和免疫功能 ;方法 选择RRTI患者 16 3例与健康儿童进行 1:1对照 ,自拟易感因素调查表 ,设 2 4个可能与RRTI有关的因素 ,由家长如实填写 ,先用逐步回归 (前进法 )筛选出影响较大的因素 ,然后进行条件定值方差分析。其中测定了 6 3例儿童RRTI测定了免疫功能指标 ,30例正常儿为对照组。结果 儿童RRTI的形成主要与胎儿期被动吸烟、胎儿期惊吓、气候变化、不合理使用抗生素及哮喘密切相关 ,血中IgG和CD3、CD4 、CD8明显降低。结论 儿童RRTI的预防要注意上述5种相关因素
Objective To study the risk factors and immunological function of children with recurrent respiratory tract infection (RRTI). Methods One hundred and sixteen patients with RRTI were selected to conduct 1: 1 comparison with healthy children. Of the factors, filled out by the parents truthfully, the first step with the gradual regression (forward method) to filter out the factors that have a greater impact, and then carry out the conditional variance analysis. Among them, 63 cases of children were measured for the determination of the immune function RRTI, 30 normal children as the control group. Results The formation of RRTI in children was mainly associated with passive smoking during fetal period, frightened fetus, climate change, unreasonable use of antibiotics and asthma. The levels of IgG, CD3, CD4 and CD8 in blood were significantly decreased. Conclusion Prevention of RRTI in children should pay attention to the above five related factors