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目的评价3种不同制剂苯磺酸氨氯地平治疗老年高血压的成本-效果。方法采用药物经济学决策树模型,构建3种苯磺酸氨氯地平治疗老年高血压的决策树,计算每种药物治疗效果的期望值,并进行敏感性分析。结果有效治疗1例老年高血压患者的期望成本,C组为574.97元,其次为A组(635.00元),B组为非优势方案。结论苯磺酸氨氯地平国产制剂短期治疗老年高血压具有较优的成本-效果,决策树模型可较好地模拟高血压短期治疗的药物经济学评价。
Objective To evaluate the cost-effectiveness of three different formulations of amlodipine besylate in the treatment of elderly hypertension. Methods Decision tree model of pharmacoeconomics was used to establish the decision tree of amlodipine besylate for senile hypertension. The expected value of each drug treatment effect was calculated and the sensitivity analysis was carried out. Results The expected cost of treating one elderly hypertensive patient effectively was 574.97 yuan in group C, followed by group A (635.00 yuan), and group B was non-dominant. Conclusion The short-term treatment of elderly patients with amlodipine besylate has better cost-effectiveness. The decision tree model can better simulate the economic evaluation of short-term treatment of hypertension.