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目的:观察更昔洛韦联合复方倍他米松治疗带状疱疹的临床疗效。方法:选取2013年3月~2015年3月之间我院收治的带状疱疹患者200例,将其随机分为对照组(100例)与观察组(100例),在外用阿昔洛韦与口服维生素B1的基础上,对照组静滴更昔洛韦治疗,观察组采用更昔洛韦联合复方倍他米松治疗,比较两组的临床疗效。结果:对照组的后遗神经痛发生率为21.0%,高于观察组的4.0%,差异显著,P<0.05,具有统计学意义;对照组治疗的总有效率为74.0%,痊愈率为53.0%,均小于观察组(总有效率95.0%,痊愈率89.0%),差异显著,P<0.05,具有统计学意义。结论:治疗带状疱疹时,采用更昔洛韦联合复方倍他米松的方式能够有效减轻疼痛感与灼烧感,促进皮损消退,预防新疱出现,疗效理想,值得推广。
Objective: To observe the clinical efficacy of ganciclovir combined with compound betamethasone in the treatment of shingles. Methods: Two hundred patients with herpes zoster admitted to our hospital from March 2013 to March 2015 were selected and randomly divided into control group (n = 100) and observation group (n = 100). Acyclovir On the basis of oral administration of vitamin B1, the control group was given intravenous ganciclovir. The patients in the observation group were treated with ganciclovir plus compound betamethasone. The clinical efficacy of the two groups was compared. Results: The incidence of postherpetic neuralgia in the control group was 21.0%, which was significantly higher than that in the observation group (P <0.05). The total effective rate in the control group was 74.0% and the cure rate was 53.0 %, Both less than the observation group (total effective rate 95.0%, cure rate 89.0%), the difference was significant, P <0.05, with statistical significance. Conclusion: In the treatment of shingles, the combination of ganciclovir and compound betamethasone can effectively reduce the pain and burning sensation, promote the subsidence of the skin lesions and prevent the appearance of new blisters, which is worthy of promotion.