论文部分内容阅读
随着细胞动力学研究的深入和化疗药物的发展,白血病的缓解率和生存率已得到了显著的改善。但由于白血病病人常有免疫缺陷,以及强烈的化疗更促使白血病患者易于合并严重感染而危及生命。其中以革蓝氏阴性杆菌引起的感染最为常见,且多为菌血症,发病突然,难以控制,往往在获得细菌培养结果以前就已死亡。合并感染已成为白血病病人死亡的重要原因之一,日益引起人们的重视。本文拟对白血病患者合并感染抗生素治疗的现状作一简要综述,试图有益于促进对这一问题的研究和解决。一、白血病患者合并感染的原因和特点 (一)粒细胞数量的减少和质的异常近年来研究表明,绝对粒细胞减少(低于1000/mm~3)是白血病患者易发感染的重要
With the deepening of cellular kinetics and the development of chemotherapeutic drugs, the remission rate and survival rate of leukemia have been significantly improved. However, patients with leukemia often have immunodeficiency and strong chemotherapy to promote leukemia patients easily combined with serious infection and life-threatening. Among them, infections caused by gram-negative bacilli are the most common and are mostly bacteremic. The incidence is sudden and difficult to control and they often die before bacterial culture results are obtained. Merger infection has become one of the important causes of death of leukemia patients, arousing more and more attention. This article intends to make a brief review of the status of treatment of leukemia patients with antibiotics combined with antibiotics, trying to help to promote the research and solution to this problem. First, the leukemia patients with infection causes and characteristics of (A) the reduction of the number of neutrophils and quality abnormalities Recent studies have shown that absolute neutropenia (less than 1000 / mm ~ 3) is an important leukemia patients prone to infection