目的探讨精子核质量与复发性流产的相关性。方法以复发性流产的男性配偶为研究对象,以健康体检男性为对照组,检测精子核蛋白不成熟度,比较两组间的差异。结果病例组54例均值为28.65±13.41%,对照组54例均值为23.37±7.60%,配对T检验P值为0.011。结论精子核蛋白不成熟度与复发性流产相关。 Objective To explore the correlation between sperm quality and recurrent spontaneous abortion. Methods Male spouses of recurrent spontaneous abortion were used as research objects, and healthy male subjects were used as control group to detect the nuclear maturation of sperm. The differences between the two groups were compared. Results The average value of 54 cases in case group was 28.65 ± 13.41%, the mean of 54 cases in control group was 23.37 ± 7.60%, and the paired T test was 0.011. Conclusions The immature sperm protein is associated with recurrent spontaneous abortion.