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帕金森病(parkinson’s disease PD)是一种神经元变性疾病,主要累及黑质致密部多巴胺能神经元。表现为多巴胺能神经元的进行性减少,虽经过上百年的研究,其病因及发病机制仍不明了。对于PD发病机制的研究主要集中在以下二个方面:①氧化应激和自由基:很多研究发现PD患者的黑质内G
Parkinson’s disease (PD) is a neurodegenerative disease that mainly affects dense substantia nigra dopaminergic neurons. The performance of dopaminergic neurons progressive decline, although after hundreds of years of research, the etiology and pathogenesis remains unclear. The pathogenesis of PD research focused on the following two aspects: ① oxidative stress and free radicals: Many studies found that patients with PD in the substantia nigra G