探讨c-erbB-2基因产物(简称产物)表达与膀胱移行细胞癌(TCC)分级、分期的关系,以及肿瘤复发与肿瘤分级、分期及c-erbB-2产物表达间的关系,采用SABC免疫组化法检测48例膀胱TCC中c-erbB-2产物的表达。实验结果显示:膀胱TCC有较高的c-erbB-2产物表达水平(54％),并与肿瘤的分级、分期有良好的相关性。c-erbB-2产物表达作为膀胱TCC的预后指标,尚有待于大样本长期的研究观察。 To investigate the relationship between the expression of c-erbB-2 gene product and the grading and staging of transitional cell carcinoma of the bladder (TCC), as well as the relationship between tumor recurrence and tumor grade, staging and c-erbB-2 product expression The expression of c-erbB-2 in 48 cases of bladder TCC was detected by histochemistry. The experimental results showed that bladder TCC had higher c-erbB-2 product expression level (54%), and had a good correlation with tumor grade and stage. c-erbB-2 product expression as a prognostic indicator of bladder TCC remains to be observed in a large sample of long-term research.