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在云南云县彝族、汉族地区用整群抽样方法对1184名自然人群进行前瞻性幽门螺杆菌（Hp）感染的血清学检测，并对其中325名同时检测抗-HAVIgG。结果发现：Hp总感染率为51．10％；彝、汉族感染率无差异。Hp感染随年龄增长而增加；饮用河水和生水明显高于饮用井水、自来水和开水；饲养家畜（禽）者明显高于未饲养者；吸毒者明显高于非吸毒者。Hp感染与HAV感染呈平行关系。多因素logistic最后筛选出饮用水源、饮水习惯、养鸡、养猪、养狗、吸毒和大蒜为Hp感染的7个重要流行因素。提示饮水是Hp感染的重要传播媒介；似支持Hp感染的动物来源理论和粪-口传播的观点；经常食用大蒜可起到长期人群防治Hp感染的作用。
A total of 1184 individuals were enrolled in the Yi and Han nationality of Yun County, Yunnan Province, for serological detection of Hp infection and 325 of them simultaneously detected anti-HAVIgG. The results showed that: the total infection rate of Hp was 51.10%; there was no difference in infection rate between Yi and Han nationality. Hp infection increased with age; drinking water and raw water was significantly higher than drinking well water, tap water and boiled water; raising livestock (poultry) were significantly higher than un-fed; drug users were significantly higher than non-drug users. Hp infection was in parallel with HAV infection. Multivariate logistic screening of drinking water sources, drinking habits, raising chickens, raising pigs, raising dogs, drug abuse and garlic for Hp infection seven important epidemic factors. Suggesting that drinking water is an important vector of Hp infection; it seems to support the animal origin theory of Hp infection and fecal-oral transmission point of view; regular consumption of garlic can play a long-term population control Hp infection.