药物性肝损伤近年呈现明显增多趋势~([1-2]),部分患者预后不良或导致死亡。在欧美等国家肝衰竭病因中药物性肝损伤占重要地位~([3-4]),在我国随着医疗卫生水平的提高,病毒性肝炎导致急性肝衰竭及死亡病例呈下降趋势,而药物性肝损伤导致急性及亚急性肝衰竭呈升高趋势~([5])。我们回顾性分析 Drug-induced liver injury in recent years showed a clear trend of increasing ~ ([1-2]), some patients with poor prognosis or cause death. In Europe and the United States and other countries the cause of liver failure drug-induced liver injury occupies an important position ([3-4]), with the improvement of medical and health level in our country, viral hepatitis causes acute liver failure and death cases showed a downward trend, and drugs Sexual liver injury leads to an increasing trend of acute and subacute liver failure ~ ([5]). We retrospectively analyzed