This paper studies the system stability problems of a class of nonconvex differential inclusions. At first, a basic stability result is obtained by virtue of locally Lipschitz continuous Lyapunov functions. Moreover, a generalized invariance principle and related attraction conditions are proposed and proved to overcome the technical difficulties due to the absence of convexity. In the technical analysis, a novel set-valued derivative is proposed to deal with nonsmooth systems and nonsmooth Lyapunov functions. Additionally, the obtained results are consistent with the existing ones in the case of convex differential inclusions with regular Lyapunov functions. Finally, illustrative examples are given to show the effectiveness of the methods.