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本品为主要由噻嗪类利尿剂、抗醛固酮剂及氨基酸类增效剂组成的复方利尿降压药。经临床应用疗效确切,副作用轻微,被认为是治疗各种原因引起的水肿及轻、中型高血压症较为理想的药物。 [作用特点] 本品为通过利尿而达到降低血压的目的。由于利尿作用使盐水排出,故导致血浆容量减少,心排出量继而降低,从而使血压下降,继续的降压作用可能通过减少交感神经兴奋的血管收缩作用,减低血管对升压物质的收缩效应,减低血管平滑肌的收缩力,直接作用于毛细血管小动脉,引起管壁水及电解质浓度的改变,从而扩张血管。由于本品采用排钾和保钾利尿剂配伍,故在服药过程中,可保持电解质平衡,无需再行补钾,减少了低血钾危险。
This product is mainly composed of thiazide diuretics, anti-aldosterone and amino acid synergist compound diuretic antihypertensive drugs. The clinical application of the exact effect of minor side effects, is considered to treat various causes of edema and mild to moderate hypertension is the ideal drug. [Features] This product is achieved through diuretic lower blood pressure purposes. Due to the diuretic effect of saline discharge, it leads to reduced plasma volume, cardiac output and then reduced, so that blood pressure, continued antihypertensive effect may be reduced by reducing sympathetic vasoconstriction, reducing blood vessels on the vasopressors contraction effect, Reduce the contractility of vascular smooth muscle, a direct role in the capillary arterioles, causing wall water and electrolyte concentration changes, which dilate blood vessels. As this product row potassium and potassium diuretics compatibility, so in the medication process, to maintain electrolyte balance, without further potassium, reducing the risk of hypokalemia.