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用原子吸收光谱分析法测定原发性肝癌、肝硬化患者血清中铁（Ｆｅ）、铜（Ｃｕ）、锌（Ｚｎ）、铝（Ａｌ）、镁（Ｍｇ）、钡（Ｂａ）、钛（Ｔｉ）等六种微量元素的变化。结果：原发性肝癌患者血清Ｃｕ、Ａｌ水平均明显增高（Ｐ＜０．００１）肝硬化组血清Ａｌ显著高于对照组（Ｐ＜０．００１），但低于原发性肝癌组（Ｐ＜０．０５）。肝癌与肝硬化组血清Ｍｇ显著低于正常组（Ｐ＜０．００１）。两组间无显著差异（Ｐ＞０．０５）。说明原发性肝癌、肝硬化的病情变化时血清Ｃｕ、Ａｌ、Ｍｇ等微量元素有一定变化。血清Ｃｕ水平均高可作为原发性肝癌诊断和预后判断的参考指标之一。
Determination of iron (Fe), copper (Cu), zinc (Zn), aluminum (Al), magnesium (Mg), barium (Ba), titanium (Ti) in serum of patients with primary liver cancer and cirrhosis by atomic absorption spectrometry The change of six kinds of trace elements. Results: Serum levels of Cu and Al in patients with primary liver cancer were significantly higher (P<0.001). Serum Al levels in patients with cirrhosis were significantly higher than those in controls (P<0.001), but lower than those in patients with primary liver cancer (P<0.001). <0.05). The serum Mg in liver cancer and liver cirrhosis group was significantly lower than that in normal group (P<0.001). There was no significant difference between the two groups (P>0.05). It shows that serum Cu, Al, Mg and other trace elements have certain changes when the condition of primary liver cancer and cirrhosis changes. The high serum Cu level can be used as a reference indicator for the diagnosis and prognosis of primary liver cancer.