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目的:微量元素与人体的健康密切相关。人体内微量元素的变化常常会反映出某种疾病的状态。肾病则是人体健康的杀手之一。探讨微量元素和慢性肾炎的关系。方法:快速电感耦合等离子体质谱(ICP-MS),同时测定血清中多个微量元素。样品加5mL浓硝酸经微波消化系统消解后可直接分析。结果:Na、K等微量元素在慢性肾炎发生时与正常组比较无显著性差异(P>0.05),而A l、Fe、Zn等则低于正常(P<0.05)。结论:根据肾病患者血清中微量元素的含量变化情况,可以为临床中肾病的治疗提供一定的指导。
Objective: Trace elements are closely related to human health. Changes in the body’s trace elements often reflect the status of a disease. Kidney disease is one of the killer of human health. To explore the relationship between trace elements and chronic nephritis. Methods: Rapid inductively coupled plasma mass spectrometry (ICP-MS) was used to determine trace elements in serum at the same time. Sample plus 5mL concentrated nitric acid digestion by microwave digestion can be directly analyzed. Results: Trace elements such as Na and K showed no significant difference (P> 0.05) when chronic nephritis occurred, while A l, Fe and Zn were lower than normal (P <0.05). Conclusion: According to the changes of trace elements in serum of patients with nephropathy, it can provide some guidance for the treatment of nephropathy in clinic.