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目的:观察血府逐瘀胶囊治疗不稳定型心绞痛患者的临床疗效及其对血脂和C反应蛋白的影响。方法:将80例患者随机分为2组各40例。对照组采用西医常规疗法;治疗组在对照组基础上加用血府逐瘀胶囊治疗,4周1疗程。结果:临床疗效总有效率治疗组90.0%,对照组65.0%,2组总有效率比较,差异有非常显著性意义(P<0.01)。2组治疗后心绞痛发作次数均减少,心绞痛持续时间均缩短,与治疗前比较,差异均有显著性意义(P<0.05);2组治疗后各项指标比较,差异均有显著性意义(P<0.05)。2组治疗后血清C-反应蛋白(CRP)、血清甘油三酯(TG)、高密度脂蛋白-胆固醇(HDL-C)水平比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。2组治疗后血清总胆固醇(TC)、低密度脂蛋白-胆固醇(LDL-C)水平比较,差异均无显著性意义(P>0.05)。结论:常规疗法联合血府逐瘀胶囊可显著降低CRP水平,改善血脂状况,对不稳定型心绞痛患者具有良好的疗效。
Objective: To observe the clinical effect of Xuefuzhuyu capsule on patients with unstable angina pectoris and its effect on blood lipids and C-reactive protein. Methods: 80 patients were randomly divided into two groups of 40 cases. The control group was treated with conventional Western medicine. The treatment group was treated with Xuefu Zhuyu Capsule on the basis of the control group, with a course of 1 week after 4 weeks. Results: The total effective rate of the treatment group was 90.0% in the treatment group and 65.0% in the control group. The total effective rate in the two groups was significantly different (P <0.01). After treatment, the number of angina attacks decreased and the duration of angina pectoris shortened, both of which were significantly different from those before treatment (P <0.05). There was significant difference between the two groups after treatment (P <0.05). The levels of serum CRP, TG and HDL-C in the two groups were significantly different between the two groups (P <0.05, P <0.01). There was no significant difference in serum total cholesterol (TC) and low density lipoprotein-cholesterol (LDL-C) between the two groups after treatment (P> 0.05). Conclusion: Conventional therapy combined with Xuefuzhuyu capsule can significantly reduce the level of CRP, improve blood lipid status and has a good effect on patients with unstable angina pectoris.