外周动脉疾病的诊断及危险因素研究进展

来源 :心血管病学进展 | 被引量 : 0次 | 上传用户:xjjuser1
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外周动脉疾病(PAD)是一系列非冠状动脉的动脉血管病变总称.诊断PAD目前比较可靠和简便的方法是踝肱指数,其标准为踝肱指数≤0.9.传统的心血管疾病危险因素中,年龄、糖尿病、吸烟和血脂异常被确认为PAD发生的独立危险因素,但具体的血脂谱中的各项脂蛋白与PAD的关系尚不明确,性别和高血压与PAD发生的关系仍有争议,肥胖却可能是保护因素.而非传统心血管疾病因素中,颈部斑块、种族差异对PAD发生的影响较为明确,纤维蛋白原也被认为与PAD的发生有较强的正相关关系,饮酒则并不增加PAD发生的风险,而肾功能、尿酸、C反应蛋白和血沉等与PAD的关系仍不明确.
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