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本文对２０例健康人和１０例溃疡病人（经奥咪拉唑２０ｍｇ／日治疗两周以上）进行研究，受试者均在口服双歧杆菌（２亿／ｄ）前及一周后各测试一次乳果糖呼氢试验。结果：服菌前健康组有４例双峰型曲线，溃疡病组均为不典型双峰曲线，服菌后两组中双峰曲线均变为单峰曲线。健康组呼气氢浓度时间曲线上Ｔ＝１３５分至２１０分各位点浓度服菌后显著增高（Ｐ＜０．０５－０．０２）溃疡病组Ｔ＝７５，９０，１０５及１９５，２１０分各位点浓度服菌一周后显著降低（Ｐ＜０．０５）。健康组服菌一周后ＦＨ２和△ＭＨ２较服菌前显著增高。结果提示：口服双歧杆菌活菌能定植于结肠内，对小肠细菌过度生长有清除作用。
In this study, 20 healthy subjects and 10 ulcer patients (treated with 20 mg omeprazole / day for more than two weeks) were enrolled. All subjects were tested before and one week after oral administration of Bifidobacterium (200 million / day) Lactulose hydrogen test. Results: There were 4 cases of bimodal curve in prematurity group and 2 cases of canonical curve in both groups. In the healthy group, the concentrations of hydrogen in the expiration time curve were significantly increased from T = 135 to 210 at each site (P <0.05-0.02), and T = 75, 90, 105 and 195, 210 The concentration of each site took a significant reduction (P <0.05). FH2 and △ MH2 in healthy group were significantly higher than those in the first week after inoculation. The results suggest that: oral Bifidobacterium viable colonization in the colon, intestinal bacterial clearance overgrowth.