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目的:就常用中药针剂对生化检验结果的影响进行探讨。方法:干扰实验药物:痰热清、脉络宁、双黄连、清开灵、香丹、茵栀黄注射液,对其进行生化检验。结果:双黄连注射液血药浓度与TG、GGT无相关性;香丹注射液与Fe、Mg、ALP、P、CRE存在着高度的正相关,可明显增高测定结果;茵栀黄注射液与CK、GLM、CO2、AST存在着高度的负相关,能够明显降低测定结果,痰热清、脉络宁、清开灵、香丹、茵栀黄也存在着相应的问题。结论:常用中药针剂会对生化检验结果造成一定的影响,应该排除药物干扰,开发出特异性更高的生化试剂,提高生化试剂的可靠性。
Objective: To discuss the influence of traditional Chinese medicine injection on biochemical test result. Methods: interfere with experimental drugs: Tanreqing, Mailuoning, Shuanghuanglian, Qingkailing, Xiangdan, Yinzhihuang injection, its biochemical tests. Results: There was no correlation between serum concentration of Shuanghuanglian injection and TG and GGT. Xiangdan injection and Fe, Mg, ALP, P and CRE had a high positive correlation, which could significantly increase the determination results. Yinzhihuang injection and CK, GLM, CO2, AST there is a high degree of negative correlation, can significantly reduce the measurement results, Tanreqing, Mailuoning, Qingkailing, Xiangdan, Yin Zhihuang there are corresponding problems. Conclusion: Commonly used Chinese medicine injection will have a certain impact on the biochemical test results, should be ruled out drug interference, the development of a higher specificity of biochemical reagents, biochemical reagents to improve reliability.