论文部分内容阅读
生存素为凋亡抑制蛋白家族新成员,具有调节细胞分裂增生和抑制细胞凋亡的双重功能,高表达于多种肿瘤组织,而在正常成人组织中未见表达。生存素参与肿瘤的发生、发展,与肿瘤预后密切相关。目前对生存素的研究已深入到信号转导通路机制。研究成果对肿瘤的诊断和治疗具有较高价值。
Survivin is a new member of the apoptosis-inhibitory protein family, which has the dual functions of regulating cell division and inhibiting apoptosis. It is highly expressed in many tumor tissues but not in normal adult tissues. Survivin is involved in the occurrence and development of tumors and is closely related to tumor prognosis. The current research on Survivin has gone deep into the signal transduction pathway. Research results on the diagnosis and treatment of tumors with high value.