健康志愿者口服H_2受体拮抗剂1到2周后,其抗酸作用显著降低。通过随机分三个治疗组来评估这种耐受性。用H_2受体拮抗剂法莫替丁,每晚饭后口服40毫克至28 After one to two weeks of oral administration of H 2 receptor antagonists, the healthy volunteers significantly reduced their antacid effect. This tolerance was assessed by randomizing the three treatment groups. With H 2 receptor antagonist famotidine, 40 mg orally after every meal to 28