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目的 探讨超声造影对转移性肝癌的诊断价值及造影增强时相特征.方法 对47例恶性肿瘤患者肝脏行常规超声检查及低机械指数超声造影检查,对肝内转移性病灶超声造影表现分析其造影增强各时相的特征.结果 47例患者常规超声共检出病灶148个,超声造影共检出357个.肝转移癌病灶增强模式可分为3型:Ⅰ型,病灶动脉期周边环状快速增强,病灶内部呈低或无增强,之后周边增强部分迅速减退;Ⅱ型,病灶于动脉期呈快速整体增强(均匀型或不均匀型)并迅速减退;Ⅲ型,病灶于动脉期呈“面包圈”样增强,门脉期增强减退呈低增强或无增强.结论 超声造影可明显提高对肝脏转移病灶检出率;其造影增强特点因其原发灶不同、血供丰富与否亦不相同.“,”Objective To evaluate the diagnostic performance of contrast-enhanced ultrasonograph (CEUS) and timing characters in liver metastasis. Methods Forty-seven patients with established primary malignancy examined by conventional ultrasound and CEUS with low mechanical index. The perfusion and echogenicity of liver metastasis were investigated using contrast tuned imaging (CnTI). The perfusion patterns of liver metastasis were analyzed. Results In 47 patients, 148 liver metastases were found by conventional ultrasound and 357 by CEUS. According to lesion characters, three contrast enhancement patterns were seen, which were type Ⅰ characterized by peripheral ring-like enhancement during the arterial phase and hyperechoic appearance during the portal venous phase and the late phase, type Ⅱ characterized by bolus-enhanced quickly and hyperechonic appearance, and type Ⅲ characterized by breadcircle enhancement during the arterial phase and hyperechoic appearance during the portal venous phase and the late phase. Conclusion CnTI can improve the diagnostic rate of liver metastases. The enhancement patterns of liver metastasi is related to primary lesion and blood perfusion.