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采用细胞贴附式膜片钳技术，观察不同浓度维那利酮对培养鸡胚心室肌细胞Ｌ－型单个钙通道电流的影响，并比较了维那利酮与米力农二者对该电流作用的异同。结果显示：不同浓度的维那利酮可增加通道的可利用率２～３倍（Ｐ＜０．００１），并使通道的开放慨率分别增加２．２５（１０￣（－５）ｍｏｌ／Ｌ）、３．０（２×１０￣（－５）ｍｏｌ／Ｌ）和４．３（１０￣（－４）ｍｏｌ／Ｌ）倍；通道的平均开放时间常数和关闭时间常数在１０￣（－５）ｓｍｏ／Ｌ和２×１０￣（－５）ｍｏｌ／Ｌ时无显著改变，而在１０￣（－４）ｍｏｌ／Ｌ组可稍延长其平均开放时间常数，缩短其平均关闭时间常数。维那利酮与同等浓度的米力农相比，二者对通道可利用率的增加程度一致，但对开放概率的增加前者比后者高出２倍。
Cell attachment patch clamp technique was used to observe the effects of different concentrations of cananalone on the current of L-type single calcium channel in cultured chick embryo ventricular myocytes. The effects of caninazolin and milrinone on the current Similarities and differences in the role. The results showed that different concentrations of cannalone increased the availability of channels by 2 to 3 times (P <0.001) and increased the open channel rate by 2.25 (10 ~ (-5) mol / 3.0, 2 × 10 -5 mol / L) and 4.3 (10 -4 mol / L) times. The average open time and shut-off time constants of the channels ranged from 10 to -5) smo / L and 2 × 10 -5 mol / L, while the average opening time constant was slightly prolonged in the 10 -4 mol / L group, and the mean closing time constant . Compared with the same concentration of milrinone, the two increased the channel availability, but increased the open probability twice as much as the latter.