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肿节风干浸膏对S-180和W-256两瘤株按4～12克干浸膏(40～120克生药)/公斤体重,连续口服7～11天使用,其抑癌率在30.5～56.7％之间。其中的琥珀酸盐(0.25～0.3克/公斤,腹腔给药9～13天)的抑癌率为30～49.4％。挥发油中的A、C部位对S-180的抑癌率为45％。它们的抗癌机理主要是抑制瘤细胞核的分裂作用。在实验中挥发油对小鼠巨噬细胞吞噬功能有抑制作用,在临床验证时应予注意。
The swollen air-dried extract used 4 to 12 grams of dry extract (40 to 120 grams of crude drug) per kilogram of body weight for S-180 and W-256 tumors and was administered orally for 7 to 11 days. The tumor inhibition rate was 30.5 to Between 56.7%. Among them, the tumor suppressing rate of succinate (0.25-0.3 g/kg, intraperitoneal administration for 9-13 days) was 30-49.4%. The tumor suppressor rate of S-180 in A and C sites in volatile oil was 45%. Their anti-cancer mechanism is mainly to inhibit the division of tumor cell nuclei. In the experiment, volatile oil can inhibit the phagocytosis of macrophages in mice, and should be noticed in clinical validation.