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目的探讨剖宫产术后镇痛对产妇泌乳素和婴儿体重的影响。方法选择期硬膜外麻醉剖宫产分娩的足月产妇６０例，随机分两组，剖宫产术后接受病人自控硬膜外镇痛（ＰＣＥＡ）为实验组，未接受ＰＣＥＡ镇痛为对照组。两组分别于剖宫产术前及术后２４、４８小时，采产妇肘静脉血２ｍｌ，采用放射免疫分析法测定血清垂体泌乳素（ＰＲＬ）值，用台称准确称婴儿出生时及出生后每日早晨的净体重。结果实验组镇痛效果明显优于对照组，实验组与对照组术前ＰＲＬ含量无差异，而剖宫产术后２４及４８小时的ＰＲＬ含量实验组明显高于对照组；（Ｐ＜００１）；实验组新生儿体重下降的幅度比对照组小（Ｐ＜００５）。结论剖宫产术后ＰＣＥＡ镇痛能够减轻产妇痛苦，促进泌乳素分泌，使婴儿体重增加。
Objective To investigate the effect of post-cesarean section analgesia on lactogen and infant’s body weight. Methods A total of 60 full-term pregnant women delivered by epidural anesthesia during cesarean section were randomly divided into two groups. PCEA was used as the experimental group after cesarean section. PCEA was used as the control group. Before and after cesarean section, 24 and 48 hours after operation, 2ml elbow venous blood was collected from the two groups, PRL was measured by radioimmunoassay. Net weight every morning. Results The analgesic effect of the experimental group was significantly better than that of the control group. There was no difference in preoperative PRL between the experimental group and the control group, while the PRL content of experimental group at 24 and 48 hours after cesarean section was significantly higher than that of the control group (P <0 01). The neonatal weight loss in the experimental group was smaller than that in the control group (P <005). Conclusion PCEA analgesia after cesarean delivery can reduce maternal pain, promote prolactin secretion and increase infant weight.