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探讨64层螺旋CT冠状动脉成像(64SCTCA)在绝经后妇女中诊断冠状动脉狭窄的性能及其应用价值。方法回顾性分析89例接受64SCTCA检查、并于4周内接受冠状动脉造影(CAG)检查的绝经1年以上妇女的临床资料，将其分为绝经10年以内(n=50)及绝经10年以上(n=39)两组，以CAG为“金标准”判断64-SCTCA诊断冠状动脉狭窄的准确性。结果64SCTCA在绝经后妇女中诊断冠状动脉狭窄的敏感性、特异性、阳性预测值、阴性预测值和诊断准确指数分别为86.46%、89.58%、66.94%、96.44%和76.04%。其在绝经10年以内的妇女中诊断冠状动脉狭窄具有更高的特异性、阴性预测值及准确性。结论64SCTCA适合于绝经后妇女用于冠状动脉狭窄的诊断，尤其适用于绝经10年内的妇女。“,”Objective To assess the diagnostic performance and clinical value of 64-slice computed tomography coronary angiography (64-SCTCA) to detect or rule out coronary heart disease (CAD) in postmenopausal women. Methods 64-slice CTA was performed in 89 postmenopausal women. The patients were divided into two groups: one that women were within 10 years after menopause and another that more than 10 years after menopause. Invasive coronary angiography was the standard of reference for coronary stenosis diagnosis. Results The Sensitivity, Specificity, positive predictive value (PPV), negative predictive value (NPV) and Youden’s index of 64-SCTCA in coronary stenosis diagnosis are 86.46%、89.58%、66.94%、96.44%和76.04% respectively. The Specificity, NPV and Youden’s index are higher in the group of women within 10 years after menopause. Conclusions 64-SCTCA has a high diagnostic accuracy in coronary stenosis diagnosis, especially for the women within 10 years after menopause.