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对60例流行性出血热患者测定了血清和尿β_(2-m)的变化,发现本病发热期血清β_(2-m)即明显高于正常,少尿期达高峰值,多尿期开始下降,至恢复期降至正常。血清β_(2-m)与BUN大致呈平行变化关系;重症组患者疾病前三期血清β_(2-m)均值皆高于轻症组。尿β_(2-m)含量的变化类似于血清β_(2-m)。这些结果说明本病肾小球与肾小管皆有损害。我们认为,若同时检测血清、尿β_(2-m)及BUN,则更能反映肾脏受损情况。
The serum and urinary β_ (2-m) levels in 60 patients with epidemic hemorrhagic fever were measured. The results showed that β_2 (2-m) was significantly higher than normal in the fever period, the peak in the oliguria period, polyuria Began to decline, to the recovery period to normal. Serum β_ (2-m) and BUN roughly parallel changes; severe disease group of patients with the first three stages of serum β_ (2-m) mean were higher than the mild group. Urinary β_ (2-m) content changes similar to serum β_ (2-m). These results indicate that the disease glomerular and tubular damage. We believe that if simultaneous detection of serum, urinary β_ (2-m) and BUN, can better reflect the situation of kidney damage.