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目的探讨社区范围内胃食管反流病(gastroesophageal reflux disease,GERD)非药物干预的效果及可行性。方法将筛选出的280例用反流性疾病诊断问卷(耐信量表,RDQ)初步确诊为GERD的患者,分为三组,非药物干预组85例,药物干预组111例,对照组84例。收集病史资料,记录观察期间RDQ值的变化。结果三组间RDQ评分有显著性差异,药物干预组症状消失者停药半年后复发46例,占总药物治疗人数的41.44%,而非药物干预组症状消失者仅有2例复发,且程度较轻。结论从近期疗效看非药物干预及药物干预皆可明显控制症状,虽然药物治疗控制症状效果好于非药物干预,但从长远看存在费用高及复发率高的情况,提示在社区范围内控制GERD疾病非药物干预是一个有效的、经济可行的好方法。
Objective To investigate the efficacy and feasibility of non-drug intervention for gastroesophageal reflux disease (GERD) in the community. Methods Two hundred and eighty patients with GERD were initially diagnosed with Reflux Disease Diagnostic Questionnaire (RDQ). They were divided into three groups: non-drug intervention group (n = 85), drug intervention group (n = 111) and control group example. Collect historical data and record changes in RDQ values during the observation period. Results There were significant differences in RDQ scores among the three groups. In the drug-intervention group, 46 patients relapsed after six months’ withdrawal, accounting for 41.44% of the total drug-treated patients, while only 2 patients relapsed after symptoms disappeared in the drug-intervention group Lighter. Conclusion From the short-term effect, non-drug intervention and drug intervention can obviously control the symptoms. Although the effect of drug control is better than non-drug intervention, the long-term existence of high cost and high recurrence rate suggests that controlling GERD Disease non-drug intervention is an effective and economically feasible method.