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下呼吸道感染是全世界范围内造成5岁以下儿童死亡的主要疾病,每年约有250万病人[10]。尽管病毒感染是小儿下呼吸道感染的重要原因,但是据世界卫生组织统计,目前约有10%～39%小儿下呼吸道感染的病因未明[13],因此,呼吸道病原学的研究对于医学界仍是一个巨大的挑战。WU多瘤病毒(WU Polyomavirus,WUPyv)是新近发现的一种人类相关多瘤病毒,由于该病毒与儿童及婴幼儿的下呼吸道感染关系密切,虽然发现不久,却引起了各国研究者的注意。
Lower respiratory tract infections are the leading cause of death worldwide in children under 5, with about 2.5 million patients annually [10]. Although viral infections are a major cause of lower respiratory tract infections in children, according to the World Health Organization, about 10% to 39% of pediatric lower respiratory tract infections are unknown at present. Therefore, the study of respiratory aetiology is still in the medical field A huge challenge. WU Polyomavirus (WUPyv) is a newly discovered human polyomavirus. Due to its close relationship with lower respiratory tract infection in children and infants and young children, WU Polyomavirus has drawn the attention of researchers from various countries.