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研究长期摄入吗啡对机体主要的免疫调控细胞Th、Ts亚群的影响和中药人参四物汤的调节作用。方法·· :流式细胞仪测定各组海洛因依赖者外周血Th、Ts亚群数目。结果··:烫吸海洛因依赖者的Th、Ts亚群数明显低于健康人群 ,服用人参四物汤组的患者 ,T细胞亚群数目有所增加 ,静脉注射海洛因依赖者的Th/Ts倒置。结论·· :海洛因依赖者的免疫功能有明显损伤 ,iv较之烫吸对T细胞损伤更甚 ,人参四物汤可缓解海洛因依赖者的免疫损伤作用。
To study the effects of long-term intake of morphine on the Th and Ts subsets of the body’s major immunoregulatory cells and the regulatory effect of the traditional Chinese medicine, Ginseng Siwu Decoction. Methods: Flow cytometry was used to measure the number of Th and Ts subsets in peripheral blood of heroin addicts in each group. Results: · The number of Th and Ts subsets in heroin addicts was significantly lower than those in healthy subjects. The number of T-cell subpopulations increased in patients taking the Panax Sintang Decoction group, and Th/Ts in IV heroin addicts was inverted. . Conclusions: : The immune function of heroin addicts is significantly impaired, and iv is more harmful to T cells than hot smoking. Ginseng Siwu Decoction can relieve the immunological damage of heroin addicts.