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经肠道传播的非甲非乙型肝炎(NANBH)的暴发流行常累及年青人,而儿童中流行及散发的经肠道传播的NANBH少见。本文报道印度某学校中9~15岁儿童暴发流行该病的情况。1988年9月4日该校当局报告前1周学校发生数例肝炎,并发现供寄宿生饮用的井水有污染。作者检测了该校所有寄宿生188人及工作人员(成人)18例的血液标本,其中67例(35.5%)儿童及4例(22%)工作人员(包括炊事员)的丙氨酸转氨酶(ALT)升高至44~200IU/L(平均120±52.1IU/L)。67例ALT升高儿童中9例有黄疸;成人中2例有黄疸;39例儿童无症状,6例有恶心或腹痛,13例有流感样症状。3例HBsAg阳性及抗-HBc
Outbreaks of enterally-transmitted non-A, non-B hepatitis (NANBH) often affect young adults, while infantile enteral transmission of NANBH is uncommon in children. This article reports the outbreak of the disease in children aged 9 to 15 years in a school in India. On September 4, 1988, a week before the school authorities reported hepatitis in the school and found that the well water for boarders was contaminated. The authors tested blood samples from 188 school-owned boarders and 18 staff members (adults), of whom 67 (35.5%) children and 4 (22%) staff (including cooks) had alanine aminotransferase (ALT ) Increased to 44-200 IU / L (average 120 ± 52.1 IU / L). Nine of 67 children with ALT had jaundice; 2 had jaundice in adults; 39 had asymptomatic children, 6 had nausea or abdominal pain, and 13 had flu-like symptoms. 3 cases of HBsAg-positive and anti-HBc