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新生儿高胆红素血症是新生儿期,尤其是新生儿早期的常见疾病,近年来文献报道发病率逐渐增多。新生儿高胆红素血症是由于胆红素在体内积聚导致皮肤、巩膜及粘膜黄染,临床上以间接胆红素升高为主,重者可引起胆红素脑病,造成神经系统损害,可能导致不同程度后遗症,即使是轻度到中度高胆红素血症也可表现为远期IQ、DQ低下,听力损坏及神经系统异常。因此,对新生儿高胆红素血症进行早期干预,以达到降低高胆红素血症的死亡率和致残率尤为重要。
Neonatal hyperbilirubinemia is a common disease in the neonatal period, especially in the early neonatal period. In recent years, the incidence of hyperbilirubinemia has been gradually increasing in the literature. Neonatal hyperbilirubinemia is due to the accumulation of bilirubin in the body lead to yellow skin, sclera and mucosa, clinically elevated indirect bilirubin, severe cases can cause bilirubin encephalopathy, resulting in nervous system damage , May lead to varying degrees of sequelae, even mild to moderate hyperbilirubinemia can also be manifested as long-term IQ, DQ low, hearing loss and nervous system abnormalities. Therefore, early intervention of neonatal hyperbilirubinemia is particularly important to reduce the mortality and morbidity of hyperbilirubinemia.