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狄戈辛是临床上最常用的强心甙之一,口服后由小肠近端吸收,吸收率约55％至75％,1.5小时血中浓度达高峰。在体内约20％至25％与蛋白结合,在肝脏代谢及进入肠—肝循环者甚少;约30％至40％以原形及其代谢产物形式自肾脏排泄。每日排出量占体存量之33％至37％,正常时其半衰期为36至48小时,老年人即使血尿素氮及肌酐浓度正常其半衰期约48小时。洋地黄毒甙口服后约8％在肝内转化为狄戈辛。西地兰的代谢与血清半衰期与狄戈辛相似。
Dioxin Xin is one of the most commonly used clinical cardiac glycosides, oral absorption by the proximal proximal intestinal absorption rate of about 55% to 75%, 1.5 hours peak blood concentration. About 20% to 25% of the body binds to proteins, metabolizes in the liver and enters the enterohepatic circulation very little; about 30% to 40% is excreted from the kidneys in the form of prototypes and their metabolites. Daily discharges account for 33% to 37% of total body volume, with a normal half-life of 36 to 48 hours. The elderly have a half-life of about 48 hours, even with normal blood urea nitrogen and creatinine concentrations. About 8% after oral administration of digoxigenin is converted to Digoxin in the liver. The metabolism and serum half-life of cedilanid are similar to Digoxigenin.