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目的:调查无视网膜病变的糖尿病和非糖尿病患者接受普通白内障手术时,应用具有前房稳定环境(CASE)和加强控制和效率(ICE)的微脉冲超乳技术对患者超乳参数和黄斑中心凹厚度(CFT)变化的影响。方法:前瞻性研究。研究包含120例患者,其中60例患者为2型糖尿病患者,设为糖尿病组(无视网膜病变),另60例设为对照组。所有患者均接受普通白内障超声乳化术。术中记录超乳参数,包括超乳时间和有效超乳时间。术前和术后1、3mo检测记录CFT并计算每次检测中CFT的差异。结果:糖尿病组的平均超乳时间为1.40±0.43min,而对照组为1.44±0.32min,差异无统计学意义(P=0.85)。糖尿病组平均有效超乳时间为20.12±8.82s,对照组为19.24±9.02s,差异无统计学意义(P=0.964)。糖尿病组术前平均CFT为218.4±12.0μm,对照组为222.1±16.6μm,差异无统计学意义(P=0.168)。术后1mo糖尿病组CFT平均增加30.3±37.2μm,对照组平均增加13.1±12.5μm。术后1mo两组CFT明显增加,糖尿病组显著高于对照组(P=0.001)。术后3mo糖尿病组和对照组的平均CFT较术前分别增加12.5±12.4μm与4.6±9.7μm。糖尿病组CFT的增加显著高于对照组(P=0.00)。但分别比较糖尿病组和对照组术后1mo至3mo平均CFT变化,会发现两组均显著减少(P=0.00,P=0.03)。结论:普通超乳手术会使CFT显著增加。糖尿病组和对照组的超乳参数相似。糖尿病组CFT变化大于对照组,但这些症状大部分表现为亚临床,并且仅显示于光学相干断层扫描(OCT)的改变。术后3mo这种变化会恢复或消失,无需治疗。
PURPOSE: To investigate the effects of hypercavity parameters and macular fovea in patients with diabetes mellitus and non-diabetic patients without cataract undergoing cataract surgery using micro-pulsatile pulsatile phacoemulsification with anterior chamber stability (CASE) and enhanced control and efficiency (ICE) Thickness (CFT) changes in the impact. Methods: Prospective study. The study included 120 patients, 60 patients with type 2 diabetes, diabetes mellitus group (no retinopathy) and the other 60 patients as control group. All patients underwent cataract phacoemulsification. Intraoperative breast hyperparathyroidism parameters, including the time of breast and effective breast milk time. CFTs were recorded before and 1, 3 months after surgery and CFT differences were calculated in each test. Results: The mean duration of phacoemulsification in diabetic group was 1.40 ± 0.43min compared with 1.44 ± 0.32min in control group, with no significant difference (P = 0.85). In the diabetic group, the average effective breast-feeding time was 20.12 ± 8.82s and that in the control group was 19.24 ± 9.02s, with no significant difference (P = 0.964). Preoperative average CFT was 218.4 ± 12.0μm in diabetic group and 222.1 ± 16.6μm in control group, with no significant difference (P = 0.168). The CFT increased by 30.3 ± 37.2μm on average in diabetic group 1mo after operation and 13.1 ± 12.5μm on average in control group. The level of CFT increased significantly in both groups at 1 month after operation, and was significantly higher in the diabetic group than in the control group (P = 0.001). The average CFT of diabetic group and control group increased by 12.5 ± 12.4μm and 4.6 ± 9.7μm respectively 3 months after operation. The increase of CFT in diabetic group was significantly higher than that in control group (P = 0.00). However, comparing the average CFT changes between 1 and 3 months in the diabetic and control groups, we found that both groups were significantly reduced (P = 0.00, P = 0.03). Conclusions: CFT was significantly increased in general mammography. Diabetes and control groups had similar breast-milk parameters. CFT changes were greater in the diabetic group than in the control group, but most of these symptoms were subclinical and showed only changes in optical coherence tomography (OCT). After 3mo this change will recover or disappear, without treatment.