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目的了解艾滋病患者继发肺癌的临床特征,为艾滋病患者继发肿瘤的防治提供依据。方法对河南豫东地区艾滋病高发县3个乡镇2003年1月至2014年12月确诊的艾滋病患者进行问卷调查和随访,并进一步结合医院病理诊断确定艾滋病患者是否继发恶性肿瘤,记录患者恶性肿瘤确诊医院和时间及治疗方法等。结果共调查894例艾滋病患者,患者家访和问卷调查均在当地艾滋病防治医疗机构负责人陪同下进行,经患者自述并就确诊和治疗医院进行逐一核对,共发现4例肺癌患者(0.447%),均为男性,艾滋病确诊年龄(48±4)岁;肺癌确诊距艾滋病确诊间隔时间(67±32)个月;4例患者均因肺癌死亡,艾滋病患者生存时间(81±32)个月,肺癌确诊距死亡时间(9±4)个月。结论艾滋病患者继发肺癌并非罕见,应加强对艾滋病患者继发恶性肿瘤的防治措施。
Objective To understand the clinical features of secondary lung cancer in AIDS patients and provide basis for the prevention and treatment of secondary cancer in AIDS patients. Methods A questionnaire survey and follow-up were conducted among three HIV / AIDS patients diagnosed in three villages and towns with high incidence of HIV / AIDS in eastern Henan from January 2003 to December 2014. The patients were further analyzed with pathological diagnosis to determine if they had secondary malignant tumor and the malignant tumor was recorded Diagnosis of hospital and time and treatment methods. Results A total of 894 AIDS patients were surveyed. The patients’ home visits and questionnaires were accompanied by the heads of local AIDS prevention and treatment institutions. Four patients with lung cancer (0.447%) were found by the patient’s self-examination and one by one checkup on the confirmed and treated hospitals. (48 ± 4) years old; the diagnosis of lung cancer was (67 ± 32) months after diagnosis of AIDS; all 4 died of lung cancer; the survival time of AIDS patients was (81 ± 32) months; lung cancer Confirmed from the time of death (9 ± 4) months. Conclusions Secondary lung cancer is not uncommon in AIDS patients. Prevention and treatment of secondary malignant tumors in AIDS patients should be strengthened.