高血压严格与非严格控制对妊娠并发症影响不明确。方法:用开放的国际多中心试验,选择妊娠14周整至33周6d的孕妇,此前无蛋白尿或妊娠高血压,诊室舒张压90~105(若孕妇正服降压药,则为85~105mm Hg,1mm Hg=0.133kPa,胎儿存活)。入选孕妇随机分为非严格控制组(舒张压靶目标100mm Hg)或严格控制组(舒张压靶目标85mm Hg)。初级终点是终止妊娠或出生后28d内加强新生儿监 Hypertension strict and non-strict control of pregnancy complications is not clear. Methods: An open international multicenter trial was conducted to select pregnant women who completed 14 weeks of gestation to 33 weeks and 6 days after having no proteinuria or pregnancy-induced hypertension. The clinic diastolic blood pressure was 90-105 (85-90% 105 mm Hg, 1 mm Hg = 0.133 kPa, fetal survival). Pregnant women were randomly assigned to either a non-strict control group (diastolic target 100 mm Hg) or a strict control group (diastolic target 85 mm Hg). Primary end point is termination of pregnancy or 28 days after birth to strengthen the neonatal supervision