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小檗碱是从植物中提取的有效成分,具有抗菌、消炎、调节血糖、降血脂、调节免疫等多种药理特性,近年来其中枢神经保护作用也成为研究的热点。小檗碱具有抗氧化和神经保护作用,有利于神经细胞生存、发展及正常功能维持,保护异常放电的脑细胞。本文就小檗碱对中枢神经系统相关疾病的治疗作用及机制的研究进展作一综述。
Berberine is an active ingredient extracted from plants and possesses a variety of pharmacological properties such as anti-bacterial, anti-inflammatory, blood sugar-regulating, anti-hyperlipidemia and immune regulation. In recent years, berberine has become a research hotspot in its central nervous system. Berberine has antioxidant and neuroprotective effects, is conducive to the survival, development and normal function of nerve cells to maintain and protect abnormally discharged brain cells. This article reviews the research progress of the therapeutic effect and mechanism of berberine on central nervous system related diseases.