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目的:探究基于音乐疗法的系统化护理应用于ICU重症肺炎患者的临床效果。方法:回顾性选取2016年1月至2018年1月在无锡市第二人民医院呼吸内科ICU进行治疗的重症肺炎患者122例作为研究对象，按照简单随机数字法分为两组，对照组(行常规护理干预)和观察组(行基于音乐疗法的系统化护理干预)，各61例。比较两组患者焦虑自评量表(SAS)、抑郁自评量表(SDS)、匹兹堡睡眠质量指数(PSQI)、急性生理与慢性健康评分系统(APACHEⅡ)评分，以及血乳酸(BLA)、氧合指数(OI)、D-二聚体、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白细胞介素-10( IL-10)水平。结果:在各项评分中，治疗前后，两组患者SAS、SDS、PSQI、APACHEⅡ评分均显著下降(n t＝16.506、17.072、8.863、7.813，8.741、11.350、6.410、4.128；均n P<0.05)；治疗后组间比较，观察组SAS、SDS、PSQI、APACHEⅡ评分显著低于对照组(n t＝7.627、7.729、2.976、5.221，均n P<0.05)。各生理指标比较，观察组OI显著高于对照组(n t＝16.506，n P<0.05)，BLA、D-二聚体、CRP、TNF-α、IL-10水平显著低于对照组(n t＝4.296、5.873、4.076、6.516、7.671，均n P<0.05)。n 结论:基于音乐疗法的系统化护理具有改善ICU重症肺炎患者焦虑、抑郁心理、睡眠质量及呼吸功能，减轻炎性反应、抑制病情发展及促进预后的效果，值得推广使用。“,”Objective:To explore the clinical effect of systemic nursing based on music therapy applied to intensive care unit(ICU) patients with severe pneumonia.Methods:Retrospectively, 122 patients with severe pneumonia from January 2016 to January 2018 were selected as the study subjects.According to the simple random number method, they were divided into two groups, the control group (routine nursing intervention) and the observation group (systematized nursing intervention based on music therapy), 61 cases in each group.Self-rating anxiety scale (SAS), self-rating depression scale (SDS), Pittsburgh sleep quality index (PSQI), acute physiology and chronic health evaluation (APACHE)Ⅱscores, blood lactate (BLA), oxygenation index (OI), D-dimer, C-reactive protein (CRP), tumor necrosis factor-α(TNF-α), interleukin-10(IL-10) levels were compared between two groups.Results:After treatment, the scores of SAS, SDS, PSQI and APACHE Ⅱ in two groups decreased significantly before treatment(n t=16.506, 17.072, 8.863, 7.813, 8.741, 11.350, 6.410, 4.128; n P<0.05). After treatment, the scores of SAS, SDS, PSQI and APACHE Ⅱ in the observation group were significantly lower than those in the control group (n t=7.627, 7.729, 2.976, 5.221, n P<0.05). OI in the observation group was significantly higher than that in the control group (n t=16.506, n P<0.05). The levels of BLA, D-dimer, CRP, TNF-α and IL-10 were significantly lower than those in the control group (n t=4.296, 5.873, 4.076, 6.516, 7.671, n P<0.05).n Conclusions:Systemic nursing based on music therapy can improve the anxiety, depression, sleep quality and respiratory function of ICU patients with severe pneumonia, reduce inflammatory response, inhibit the development of the disease and promote the recovery of prognosis, which is worthy of promotion and use.