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对于患有威胁胎儿宫内发育疾病的孕妇,判断其胎儿健康情况,选定适宜时间分娩以减低婴儿围产期死亡,是产科工作中一项重要课题。孕妇尿中雌激素是胎儿体内雌激素的前驱物质,经胎盘转化为雌三醇自母体肾脏排出。近20多年很多文献报告关于探索简易测定孕妇尿雌三醇作为估计胎儿宫内健康情况的指标。我们采用了北医生理教研组提出的改良Bra-mhall氏的尿雌三醇快速荧光测定法稍加改进,一年多来用于高危妊娠测验胎儿健康情况,认为是协助临床处理的一种简捷、可信赖的试验方法。
It is an important issue in obstetric work for a pregnant woman who has threatened fetal intrauterine development to determine its fetal health status and select the appropriate time for childbirth to reduce perinatal death. Urinary estrogen in pregnant women is a precursor of estrogen in the fetus, excreted from the mother’s kidney through the placenta into estriol. In the past two decades, many reports on the exploration of simple determination of urinary estriol in pregnant women as an indicator of fetal health status. We used the Northern Medical Science Teaching and Research Group proposed improved Bra-mhall ’s urinary estriol rapid fluorescence assay slightly improved more than a year for high-risk pregnancy test fetal health, that is to help clinical treatment of a simple, Trusted test methods.